EMBnet MCB, feb 2005 An introduction to biological databases Marie-Claude.Blatter@isb-sib.ch EMBnet MCB, feb 2005 What is a database ? Secondary Databases: Those data that are derived from the analysis or treatment of primary data such as secondary structures, hydrophobicity plots, and domain are stored in secondary databases c) Atlas of protein sequence and structure. b) PDB. a) SWISS PROT. d) Protein sequence databank. Secondary biological databases, however, summarize the results from analyses of primary protein sequence databases. WHAT ARE THE BIOLOGICAL DATABASES ??? d) ticket. Primary data is a type of data that is collected by researchers directly from main sources through interviews, surveys, experiments, etc. Primary databases contain primary sequence information (nucleotide or protein) and accompanying annotation information regarding function, bibliographies, cross-references to other databases, etc. Typesof BiologicalDatabases • On the basis of source: Primary Databases Secondary Databases 7. c) record. Margaret Dayhoff developed the first protein sequence database called. They provide a computational support and a user-friendly interface to a researcher for a meaningful analysis of biological data. Primary databases store and make data available to the public, acting as repositories. 8 9. Literature databases include. 9 10. NK BioSoft Provides Free Life Sciences, Agricultural Sciences Books, Journals, Softwares, Biological Documentries, Biological Calculators, Animated Tutorials and List of Major Biological Search Engines. 6.2 Primary sequence databases 6.2.1 Introduction In the early 1980’s, several primary database projects evolved in different parts of the world (see table 6.1). Databases and Different types of Biological Databases Definition: A collection of related data arranged in a way suitable for adding, locating, removing and modifying the data The database which store biological data is called biological database Eg: nucleotide sequence database • A collection of – structured – searchable (index)-> table of contents – updated periodically (release)-> new edition – cross-referenced (hyperlinks) -> … 2. Biological Databases serve a critical purpose in the collation and organization of data related to biological systems. It is an India's Largest Biological WebPortal Created for Providing Free Facilities to Research Scholars, Students, Teachers and Other Who Want to Work with Life Sciences. Primary data are usually collected from the source—where the data originally originates from and are regarded as the best kind of data in research. Each record in a database is called an. There are two main classes of databases:DNA (nucleotide) databases and protein databases. Biological Databases: 1. Databases consisting of data derived experimentally such as nucleotide sequences and three dimensional structures are known as primary databases. a) entry. Biological databases are centralised resources that contain representations of DNA and protein sequences and their associated information. • Experimental results are submitted directly into the database by researchers, … b) file. Various biological databases are available online, which are classified based on various criteria for ease of access and use. 3. DNA (nucleotide) Protein The primary sequence databases have grown tremendously over the years. What is Primary Data? Primary Databases • They contains biomolecular data in its original form.

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